CNN's lead DC anchor and chief Washington correspondent, Jake Tapper, hosts this two-hour long weekday afternoon program, with headlines from around the country and the world, the top stories in national and international news, politics, health, money, the environment, sports and popular culture. The Lead also concentrates on bringing stories that aren't found on front pages—buried leads—to the forefront.

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Title Date published
Biden: “Trump panicked; The virus was too big for him”; U.S. approaches 200,000 deaths from COVID-19; Trump speaks about Supreme Court vacancy; Dems need two more GOP senators to block Trump’s nominee 2020-09-21
Trump claims there will be enough doses of COVID-19 vaccine for every American by April 2021; Biden: This campaign is Scranton vs. Park Avenue; Mary Trump reacts to Woodward & Troye revelations; 2020-09-18
Biden, Harris, Pence make Labor Day visits to battleground states; Labor Day crowds drive fears of new virus spikes; CA breaks record for acres burned statewide in a year; U.S. performed 740,000+ COVID tests in the last week; 2020-09-07
New CNN poll: Biden tops Trump 51% to 43%; 17 states report upticks in new cases; Pelosi on criticism over salon visit: “it was a set up”; Trump pushes “law & order” message amid unrest 2020-09-02
Chief of staff defends Trump’s use of White House in convention; Source: CDC recommending fewer people be tested after pressure from the “top” of Trump administration; All NBA playoff games postponed tonight after Jacob Blake shooting 2020-08-26
Biden accepts Dem nomination in career-defining speech; Trump claims vote by mail will be a “catastrophe”; Postal Chief: No plans to bring back removed sorting machines; CDC predicts nearly 195,000 COVID deaths in U.S. by Sept. 12; 2020-08-21
Infectious disease expert: We need another lockdown; One-on-one with Trump’s testing Czar; Trump promotes baseless birther lie about Kamala Harris; Obama: Trump trying to “actively kneecap” the Postal Service; 2020-08-14
Sources: Biden long believed Harris was strongest choice; Trump reverts to stereotypes as campaign struggles to respond to Harris; Biden, Harris appear together for first time as running mates 2020-08-12
Breaking News: Biden picks Sen. Kamala Harris as running mate 2020-08-11
New model: U.S. death toll could reach nearly 300,000 by December; Ohio governor speaks after positive COVID-19 test; Some Senators leave town with no relief deal for struggling Americans; What’s driving Biden’s running mate decision; 2020-08-06
Fauci: state of testing in the U.S. “unacceptable, period”; Partisan fight over stimulus bill leaves millions of Americans in limbo, struggling; Georgia 2nd grader tests positive after first day of school 2020-08-05
Trump on COVID-19 death toll: “It is what it is”; Health Minister: At least 50 dead, 2,750+ injured in Beirut blast; Trump: Virus “under control as much as you can control it”; Sources: WH, top Dems nowhere near deal on stimulus bill; 2020-08-04
W.H.O.: there may never be a pandemic “silver bullet”; Trump attacks Birx after she said virus is “widespread” in U.S.; New report examines “how the pandemic defeated America”; Trump: U.S. will soon see great treatments & vaccine; 2020-08-03
U.S. tops 4.5 million cases; nearly 153,000 deaths from COVID-19; Trump in Florida as coronavirus deaths hit new record & hurricane moves in; Postal Service: “We’re not slowing down election mail”; CDC: 260 kids and staff infected at Georgia camp; 2020-07-31
Biden addresses systemic racism in economic speech; AG Barr spars with Dem lawmakers in contentious hearing; Fauci, Birx concerned about virus spikes in OH, IN, TN & KY; Trump promotes reckless claims on coronavirus, renews attack on Dr. Anthony Fauci; 2020-07-28
Fauci: all options must be on the table in fighting virus; Amid sinking polls, Trump tries to rewrite virus response; Ohio coronavirus hospitalizations hit record high; Washington among 25 states seeing a rise in cases; 2020-07-24
Death toll Tuesday topped 1,000 for first time in two weeks; U.S. signs $1.95 billion deal with Pfizer for vaccine; Dem mayors to Trump admin: no federal forces in our cities; Republicans split on plans for new stimulus package 2020-07-22
Three vaccine trials show early promising results; Trump downplays virus threat, reappears claim it will “disappear”; Florida reporting more than 10,000 new COVID-19 cases; Los Angeles County breaks daily record for hospitalizations; 2020-07-20
Fauci says WH efforts to undermine him were "bizarre"; CDC estimates 20m cases in the U.S., when only 2m were diagnosed; Is it safe to send your kids to school in the fall?; Mary Trump: the president paid someone to take the SAT for him 2020-07-15
Florida hits single day death record from COVID-19; Utah man dies in line waiting for coronavirus test; Trump’s coronavirus approval rating hits all-time low; Trump: More white people are killed by police than black people; 2020-07-14
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