From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing.
Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story. If you’re curious, skeptical, and you like learning in public — you’re in the right place.
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Artemis II, Claude Code Leak, iPhone Spyware & Project Hail Mary (EP 36)
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2026-04-03
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Can AI Help Wake Coma Patients? The Science of Consciousness (EP 35)
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2026-03-31
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AI Cancer Vaccines, Strange Fish, Ketamine, and Ancient Life (EP. 34)
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2026-03-27
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Can Human Neurons Really Play Doom? The Science Behind Wetware (EP. 33)
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2026-03-24
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5,000-Year-Old Bacteria, Solar Storms, Dogs, and Meta’s AI War (EP. 32)
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2026-03-20
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Optovolution: Teaching Proteins to Think Like Computers (EP. 31)
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2026-03-18
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Can We Stop an Asteroid? The Physics Behind NASA’s DART Mission (EP. 30)
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2026-03-16
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Astrobiology’s Biggest Survival Test + A Vaccine Against Everything? (EP. 29)
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2026-03-12
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Dark Galaxies, Fuzzy Dark Matter, and an Alzheimer’s Breakthrough (EP. 28)
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2026-03-04
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Dream Engineering, the Proton Radius Puzzle, and an ALS Breakthrough (EP. 27)
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2026-02-26
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Winter Olympics Deep Dive: Ice Physics, Performance Pressure, and Climate Change (EP. 26)
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2026-02-18
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Plants, Quantum Sensors, and Predicting Cancer Evolution (EP. 25)
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2026-02-10
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Artemis II, Apollo, and the Physics of Going Back to the Moon (EP. 24)
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2026-02-04
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JWST’s “Little Red Dots,” TimeVaults, and the Dawn of Math (EP. 23)
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2026-01-27
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Cloud9 Dark Matter Halo, Jellyfish Sleep, and String Theory Hidden in Nature (EP. 22)
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2026-01-20
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Roman Concrete, Brain “Cognitive Legos,” DeepSeek, and Econophysics (EP. 21)
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2026-01-12
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The Physics Behind Fusion’s Biggest Problem (Season Finale) (EP. 20)
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2025-12-23
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The Race to the Double Helix — Watson, Crick, Franklin & the Real Story of DNA (EP. 19)
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2025-12-04
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3I/ATLAS Explained, Forensic Fingerprints & Alzheimer’s Breakthrough (EP. 18)
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2025-11-27
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Hypersonic Physics, Deep Sea Life & Princeton’s Millisecond Qubits (EP. 17)
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2025-11-22
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